• [ Pobierz całość w formacie PDF ]
    Animal Transgenesis and Cloning.
    Louis-Marie Houdebine
    Copyright ¶ 2003 John Wiley & Sons, Ltd.
    ISBNs: 0-470-84827-8 (HB); 0-470-84828-6 (PB)
    Animal Transgenesis
    and Cloning
    Animal Transgenesis
    and Cloning
    Louis-Marie Houdebine
    Institut National de la Recherche Agronomique,
    Jouy en Josas, France
    Translated by
    Louis-Marie Houdebine, Christine Young,
    Gail Wagman and Kirsteen Lynch
    First published in French as TransgenÁse Animale et Clonage # 2001 Dunod, Paris
    Translated into English by Louis-Marie Houdebine, Christine Young, Gail Wagman and
    Kirsteen Lynch.
    This work has been published with the help of the French Minist
    Á
    re de la Culture-Centre
    national du livre
    English language translation copyright # 2003 by John Wiley & Sons Ltd,
    The Atrium, Southern Gate,
    Chichester, West Sussex, PO19 8SQ,
    England
    National 01243 779777
    International (44) 1243 779777
    e-mail (for orders and customer service enquiries):
    cs-books@wiley.co.uk
    Visit our Home Page on http://www.wileyeurope.com
    or http://www.wiley.com
    All rights reserved. No part of this publication may be reproduced, stored in a retrieval system,
    or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording,
    scanning or otherwise, except under the terms of the Copyright, Designs and Patents Act 1988
    or under the terms of a licence issued by the Copyright Licensing Agency, 90 Tottenham Court
    Road, London, UK W1P 9 HE, without the permission in writing of the publisher.
    Other Wiley Editorial Offices
    John Wiley & Sons, Inc., 111 River Street,
    Hoboken, NJ 07030, USA
    Wiley-VCH Verlag GmbH, Pappelallee 3,
    D-69469 Weinheim, Germany
    John Wiley & Sons (Australia) Ltd, 33 Park Road, Milton,
    Queensland 4064, Australia
    John Wiley & Sons (Asia) Pte Ltd, 2 Clementi Loop #02-01,
    Jin Xing Distripark, Singapore 0512
    John Wiley & Sons (Canada) Ltd, 22 Worcester Road,
    Rexdale, Ontario M9W 1L1, Canada
    Wiley also publishes in books in a variety of electronic formats. Some content that appears
    in print may not be available in electronic books.
    Library of Congress Cataloguing-in-Publication Data
    applied for
    British Library Cataloguing in Publication Data
    A catalogue record for this book is available from the British Library
    ISBN 0-470-84827-8 (Hardback)
    0-470-84828-6 (Paperback)
    Typeset in 10/13 pt Times by Kolam Information Services Pvt. Ltd., Pondicherry, India
    Printed and bound in Great Britain by TJ International, Padstow, Cornwall
    This book is printed on acid-free paper responsibly manufactured from sustainable forestry,
    in which at least two trees are planted for each one used for paper production.
    Contents
    Introduction
    ix
    Abbreviations and Acronyms
    xiii
    1 From the gene to the transgenic animal
    1
    1.1 Genome composition
    1
    1.2 Gene structure
    4
    1.3 The number of genes in genomes
    7
    1.4 The major techniques of genetic engineering
    13
    1.4.1 Gene cloning
    13
    1.4.2 DNA sequencing
    14
    1.4.3 In vitro gene amplification
    14
    1.4.4 Gene construction
    14
    1.4.5 Gene transfer into cells
    16
    1.5 The systematic description of genomes
    21
    1.6 Classical genetic selection
    26
    1.7 Experimental mutation in genomes
    27
    1.7.1 Chemical mutagenesis
    27
    1.7.2 Mutagenesis by integration of foreign DNA
    29
    1.7.3 Mutagenesis by transgenesis
    30
    2 Techniques for cloning and transgenesis
    33
    2.1 Cloning
    33
    2.1.1 The main steps of differentiation
    33
    2.1.2 Cloning by nuclear transfer
    37
    2.2 Gene therapy
    48
    2.2.1 The goals of gene therapy
    48
    2.2.2 The tools of gene therapy
    49
    2.2.3 The applications of gene therapy
    52
    2.3 Techniques of animal transgenesis
    54
    2.3.1 The aims and the concept of animal transgenesis
    54
    2.3.2 Gene transfer into gametes
    60
    [ Pobierz całość w formacie PDF ]

  • zanotowane.pl
  • doc.pisz.pl
  • pdf.pisz.pl
  • wzory-tatuazy.htw.pl